2026
Del Carmen-Fabregat A, Oswal N, Sinha K, Vicencio J, Abramowitz R, Eder M, Begik O, Sedlackova L, Novoa E, Stroustrup N. Declines in mRNA synthesis set the rate of organismal aging. bioRxiv [Full Text]
D’Angelo, A., Franco-Barranco, D., Musy, M. Duran J, Sharpe J, Stroustrup N, Arganda Carreras I, Boke E. Three-dimensional mapping of intact ovaries reveals the aging dynamics of the ovarian reserve. Nature Aging. 6, 1580–1591 (2026). [Full Text]
Pradhan S, Stojanovski K, Dellemann F, Psalmon S, Tuomaala J, Stroustrup N, Towbin B. Dietary restriction shapes intergenerational ribosome abundance and early growth of Caenorhabditis elegans offspring. PLoS Biology (2026)
2023-2025
Eder M, Stroustrup N. STOMP-seq: early multiplexing for high-throughput SMART RNA-sequencing. bioRxiv (2025) [Full Text]
Vicencio J, Chihara D, Eder M, Ahringer J, Stroustrup N. Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology. Nature Communications (2025) [Full Text]
Mosley M, Kinser H, Martin OMF, Stroustrup N, Schedl T, Kornfeld K, Pincus Z. Similarities and differences in the gene expression signatures of physiological age versus future lifespan. Aging Cell (2024)
, , , , , , . Selective autophagy of ribosomes balances a tradeoff between starvation survival and growth resumption. BioRxiv (2024)
Eder M, Martin O.M.F, Oswal N, Sedlackova L, Moutinho C, Del Carmen-Fabregat A, Menendez Bravo S, Sebé-Pedrós A, Heyn H, Stroustrup N. Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony. Cell (2024) [Full Text]
Al-Refaie N, Padovani F, Hornung J, Pudelko L, Binando B, del Carmen Fabregat A, Zhao Q, Towbin B, Sarinay Cenik E, Stroustrup N, Padeken J, Schmoller S & Cabianca D. Fasting shapes chromatin architecture through an mTOR/RNA Pol I axis. Nature Cell Biology (2024)
del Carmen Fabregat A, Sedlackova L, Oswal N, Stroustrup N. High-throughput Behavioral Aging and Lifespan Assays using the Lifespan Machine. Journal of Visual Experiments, 203. (2024)
2020-2022
Natasha Oswal, Olivier M.F. Martin, Sofia Stroustrup, Monika A.M. Bruckner, Stroustrup, N. A hierarchical process model links behavioral aging and lifespan in C. elegans. PLOS Computational Biology (18) 9 e1010415. (2022) [Full Text]
Cohen, Alan A; Ferrucci, Luigi; Fülöp, Tamàs; Gravel, Dominique; Hao, Nan; Kriete, Andres; Levine, Morgan E; Lipsitz, Lewis A; Olde Rikkert, Marcel GM; Rutenberg, Andrew, Stroustrup, N; Varadhan, Ravi. A complex systems approach to aging biology. Nature Aging 2 (7),580-591 (2022) [Full Text]
Cutler, Kevin J; Stringer, Carsen; Lo, Teresa W; Rappez, Luca; Stroustrup, N; Brook Peterson, S; Wiggins, Paul A; Mougous, Joseph D. Omnipose: a high-precision morphology-independent solution for bacterial cell segmentation. Nature Methods 19 (11), 1438-1448 (2022)
Servello, Francesco A; Fernandes, Rute; Eder, Matthias; Harris, Nathan; Martin, Olivier MF; Oswal, Natasha; Lindberg, Anders; Derosiers, Nohelly; Sengupta, Piali; Stroustrup, N; Apfeld, Javier. Neuronal temperature perception induces specific defenses that enable C. elegans to cope with the enhanced reactivity of hydrogen peroxide at high temperature. Elife. 11 e78941 (2022)
Jodie A Schiffer, Francesco A Servello, William R Heath, Francis Raj Gandhi Amrit, Stephanie V Stumbur, Matthias Eder, Olivier MF Martin, Sean B Johnsen, Julian A Stanley, Hannah Tam, Sarah J Brennan, Natalie G McGowan, Abigail L Vogelaar, Yuyan Xu, William T Serkin, Arjumand Ghazi, Stroustrup, N, Javier Apfeld. Caenorhabditis elegans processes sensory information to choose between freeloading and self-defense strategies. Elife. 9:e56186. (2020)
2018-2019
Janssens, Georges E., Xin-Xuan Lin, Lluis Millan-Arino, Alan Kavšek, Ilke Sen, Renée I. Seinstra, Stroustrup, N, Ellen AA Nollen, and Christian G. Riedel. Transcriptomics-based screening identifies pharmacological inhibition of Hsp90 as a means to defer aging. Cell Reports 27, no. 2 467-480. (2019)
Stroustrup, N. Measuring and modeling interventions in aging. Curr. Opinion in Cell Biology, 55 (2018) [Full Text]
Lin X, Sen I, Janssens G, Zhou X, Fonslow B, Edgar D, Stroustrup N, Swoboda P,Yates J, Ruvkun G, Riedel C. DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity. Nature Communications 9 4400 (2018)
2016-2017
William B Zhang, Drew B Sinha, William E Pittman, Erik Hvatum, Stroustrup, N, Zachary Pincus. Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health. Cell Systems (2016) 333-345. e4
McEwan, Deborah L., Rhonda L. Feinbaum, Stroustrup, N, Wilhelm Haas, Annie L. Conery, Anthony Anselmo, Ruslan Sadreyev, Frederick M. Ausubel. Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway. BMC biology (2016)
Select Previous Work
Stroustrup N, Anthony W, Nash Z.M, Gowda V, Gomez A, López-Moyado I.F, Apfeld J, Fontana W
The temporal scaling of C. elegans ageing. Nature, 530, 103-107 (2016) [Full Text]
Stroustrup N, Ulmschneider B. E. , Nash Z. M. , López Moyado I. F., Apfeld J, and Fontana W. The C. elegans Lifespan Machine. Nature Methods, 10, 665-670 (2013) [Full Text]
Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch’ng Q. An Insulin-to-Insulin Regulatory Network Orchestrates Phenotypic Specificity in Development and Physiology. PLOS Genetics (2014)