2024-2023
Vicencio J, Chihara D, Eder M, Ahringer J, Stroustrup N. Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology. BioRxiv (2024) [Full Text]
Eder M, Martin O.M.F, Oswal N, Sedlackova L, Moutinho C, Del Carmen-Fabregat A, Menendez Bravo S, Sebé-Pedrós A, Heyn H, Stroustrup N. Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony. Cell (2024) [Full Text]
Al-Refaie N, Padovani F, Hornung J, Pudelko L, Binando B, del Carmen Fabregat A, Zhao Q, Towbin B, Sarinay Cenik E, Stroustrup N, Padeken J, Schmoller S & Cabianca D. Fasting shapes chromatin architecture through an mTOR/RNA Pol I axis. Nature Cell Biology (2024)
del Carmen Fabregat A, Sedlackova L, Oswal N, Stroustrup N. High-throughput Behavioral Aging and Lifespan Assays using the Lifespan Machine. Journal of Visual Experiments, 203. (2024)
2022-2020
Natasha Oswal, Olivier M.F. Martin, Sofia Stroustrup, Monika A.M. Bruckner, Stroustrup, N. A hierarchical process model links behavioral aging and lifespan in C. elegans. PLOS Computational Biology (18) 9 e1010415. (2022) [Full Text]
Cohen, Alan A; Ferrucci, Luigi; Fülöp, Tamàs; Gravel, Dominique; Hao, Nan; Kriete, Andres; Levine, Morgan E; Lipsitz, Lewis A; Olde Rikkert, Marcel GM; Rutenberg, Andrew, Stroustrup, N; Varadhan, Ravi. A complex systems approach to aging biology. Nature Aging 2 (7),580-591 (2022) [Full Text]
Cutler, Kevin J; Stringer, Carsen; Lo, Teresa W; Rappez, Luca; Stroustrup, N; Brook Peterson, S; Wiggins, Paul A; Mougous, Joseph D. Omnipose: a high-precision morphology-independent solution for bacterial cell segmentation. Nature Methods 19 (11), 1438-1448 (2022)
Servello, Francesco A; Fernandes, Rute; Eder, Matthias; Harris, Nathan; Martin, Olivier MF; Oswal, Natasha; Lindberg, Anders; Derosiers, Nohelly; Sengupta, Piali; Stroustrup, N; Apfeld, Javier. Neuronal temperature perception induces specific defenses that enable C. elegans to cope with the enhanced reactivity of hydrogen peroxide at high temperature. Elife. 11 e78941 (2022)
Jodie A Schiffer, Francesco A Servello, William R Heath, Francis Raj Gandhi Amrit, Stephanie V Stumbur, Matthias Eder, Olivier MF Martin, Sean B Johnsen, Julian A Stanley, Hannah Tam, Sarah J Brennan, Natalie G McGowan, Abigail L Vogelaar, Yuyan Xu, William T Serkin, Arjumand Ghazi, Stroustrup, N, Javier Apfeld. Caenorhabditis elegans processes sensory information to choose between freeloading and self-defense strategies. Elife. 9:e56186. (2020)
2019-2018
Janssens, Georges E., Xin-Xuan Lin, Lluis Millan-Arino, Alan Kavšek, Ilke Sen, Renée I. Seinstra, Stroustrup, N, Ellen AA Nollen, and Christian G. Riedel. Transcriptomics-based screening identifies pharmacological inhibition of Hsp90 as a means to defer aging. Cell Reports 27, no. 2 467-480. (2019)
Stroustrup, N. Measuring and modeling interventions in aging. Curr. Opinion in Cell Biology, 55 (2018) [Full Text]
Lin X, Sen I, Janssens G, Zhou X, Fonslow B, Edgar D, Stroustrup N, Swoboda P,Yates J, Ruvkun G, Riedel C. DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity. Nature Communications 9 4400 (2018)
2017-2016
William B Zhang, Drew B Sinha, William E Pittman, Erik Hvatum, Stroustrup, N, Zachary Pincus. Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health. Cell Systems (2016) 333-345. e4
McEwan, Deborah L., Rhonda L. Feinbaum, Stroustrup, N, Wilhelm Haas, Annie L. Conery, Anthony Anselmo, Ruslan Sadreyev, Frederick M. Ausubel. Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway. BMC biology (2016)
Select Previous Work
Stroustrup N, Anthony W, Nash Z.M, Gowda V, Gomez A, López-Moyado I.F, Apfeld J, Fontana W
The temporal scaling of C. elegans ageing. Nature, 530, 103-107 (2016) [Full Text]
Stroustrup N, Ulmschneider B. E. , Nash Z. M. , López Moyado I. F., Apfeld J, and Fontana W. The C. elegans Lifespan Machine. Nature Methods, 10, 665-670 (2013) [Full Text]
Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch’ng Q. An Insulin-to-Insulin Regulatory Network Orchestrates Phenotypic Specificity in Development and Physiology. PLOS Genetics (2014)